Endocrine Abstracts

Background: Impaired health related quality of life (QOL) in patients in long-term remission of Cushing’s syndrome (CS) has previously been reported. However, the major determinants of the impaired QOL have not yet been established.Aim: To investigate QOL of patients in long-term remission of CS treated in our hospital (1969–2007) and to investigate the influence of the etiology of CS, treatment strategy, coexistent hypopituitarism and glucocor...

Aim: The changes in serum oestradiol levels in assigned female at birth (AFAB) transgender people receiving testosterone therapy have not been elucidated. How serum oestradiol levels change after initiation of testosterone therapy, if these levels should be monitored and whether altered oestradiol levels will result in adverse health outcomes, remains unclear.Methods: This prospective cohort study was part of the European Network for the Investigation of...

Aim: Anger is a state of emotions ranging from irritation to intense rage. Aggression is the externalization of anger through destructive/punitive behaviour. The World Professional Association for Transgender Health (WPATH) Standards of Care, Edition 7 (SOC7) guidelines warn about aggression in transgender men (TM) on testosterone treatment. We aimed to assess whether aggression and anger intensity increase in TM and decrease in transgender women (TW) after initiation of gende...

Background: Primary hyperparathyroidism (pHPT) is the most prevalent manifestation of multiple endocrine neoplasia type 1 (MEN1). Surgery is the preferred treatment but which type of surgery offers the best chance of cure combined with the lowest risk of postoperative hypoparathyroidism is still uncertain.Aims: Identifying the optimal surgical technique for MEN1 related pHPT. Describing the course of postoperative hypoparathyroidism. To see if a genotype...